Dr. Eva Garland appearing on WCOM radio on April 29, 2014. Dr. Garland discussed her book “Winning SBIR/STTR Grants: A Ten Week Plan for Preparing Your NIH Phase I Application”. SBIR vs STTR: which small business research grant fits your stage
Photo by GarlandFamily on Wikimedia Commons, CC BY-SA 3.0

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SBIR vs STTR: which small business research grant fits your stage

SBIR vs STTR eligibility turns on one rule: STTR needs a nonprofit research partner. Here is how the two federal research grants differ by company stage.

What to take away

  • SBIR pays one small business to run its own research. STTR requires a nonprofit research partner that performs at least 30 percent of the work.
  • Size and ownership tests are identical in both: for-profit, United States-based, 500 or fewer employees counting affiliates.
  • Eleven agencies run SBIR and five run STTR, which narrows your options before anything else does.
  • If the science sits in a university lab, check STTR first. If your own staff holds the expertise, SBIR is the shorter path.

Where the two programs divide

Both programs sit in the same statutory family and are coordinated by the U.S. Small Business Administration. The official SBIR program overview sets the shared floor: for-profit, United States-based, 500 or fewer employees counting affiliates, and ownership largely held by citizens or permanent residents.

The split appears one step later. SBIR has no partner requirement. STTR does, and that single rule changes who applies, who performs the work, and how much paperwork precedes a submission. Companies often learn this from a rejection, one of the federal grant mistakes that costs a full solicitation window.

The criteria that matter

Criterion SBIR STTR
Research partner None required Required, and must be a nonprofit research institution
Work split Small business performs most of the research Partner performs at least 30 percent, small business at least 40 percent
Principal investigator Must be primarily employed by the small business May be employed by the small business or the research partner
Participating agencies 11, including USDA, DoD, HHS, DOE, NASA and NSF 5: DoD, DOE, HHS, NASA and NSF
Typical Phase I award Illustrative range of $150,000 to $300,000 Same range, set agency by agency

Each agency writes its own solicitation, so this table is a floor rather than the whole test. Ownership, registration and cost share are among the items in what federal grants require before review begins.

An STTR proposal is read together with the partner terms. Agencies expect the allocation of intellectual property rights to be settled before award, not after.

Option by option

SBIR suits a company that already employs its researchers. The principal investigator draws a paycheck from the business, the research stays in house, and the company holds its intellectual property outright. SBA publishes agency-by-agency tutorials on how each one structures Phase I and Phase II.

STTR suits a company built around someone else's laboratory. A faculty founder, a shared instrument, or years of prior work at a research institute all point the same way. The trade is real: the partner performs part of the research, and the rights are settled in writing before submission.

Where each one wins

SBIR wins when speed and control matter most. A five-person firm with an engineer founder can approach any of eleven agencies without signing a partner agreement first.

STTR wins when the science depends on equipment or expertise the company does not own. A diagnostics startup spun out of a university lab is the standard case. The partner's 30 percent is a contribution, not a fee.

Agency choice often matters more than program choice. The Department of Defense issues most of its awards as contracts, while the National Science Foundation and the National Institutes of Health issue grants. Contract terms bring federal acquisition rules with them.

What none of them solve

Neither program funds a business that is not doing research. Both are competitive, phase-gated and slow, and neither pays anything until you win. Review timelines that run for months are normal.

Registration is the other shared hurdle. A Unique Entity Identifier from SAM.gov and the agency portal accounts take weeks to clear, and federal grant eligibility basics are verified before any proposal is read. Indirect cost treatment varies by agency, which is why the federal grants cost picture shifts from one solicitation to the next.

Common questions

Do I need a university for STTR? No. Universities qualify, but so do other nonprofit research institutions and federally funded research and development centers. Some projects pair with a small college or a nonprofit institute instead. The test is the partner's status, not its name.

Can a professor serve as principal investigator? Under STTR, yes, when the professor is employed by the research partner. Under SBIR, the investigator must be primarily employed by the small business.

Can one company hold both an SBIR award and an STTR award? Yes, often with different agencies. Agencies do restrict duplicate submissions of essentially the same proposal, so read the solicitation before sending the same science to two places. A second submission through another agency is treated as a new proposal with its own budget.

How early should I start? Months ahead. Agencies publish topics on their own calendars, and a grant alert feed built on source pages beats a general newsletter. Registration alone can take three to four weeks.

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